一、个人简介
理学博士，教授，科创拔尖人才，泰山学者青年专家。2022年6月博士毕业于山东大学，师从国家杰青孙金鹏教授，2022年9月起任职于山东第一医科大学。
二、研究方向
主要研究领域为粘附类G蛋白偶联受体结构药理学，包括粘附类GPCR内源性配体识别及激活机制相关研究。
三、项目、获奖及荣誉情况概述
相关成果以leading author身份分别发表在2篇国际期刊Nature杂志。首次解析了粘附类GPCR七次跨膜螺旋结构，发现了糖皮质激素膜受体，阐明受体被配体识别与激活机制（Nature. 2021 Jan; 589(7843):620-626）。揭示了粘附类受体的自激活机制及对机械力感知的结构基础（Nature. 2022 Apr; 604(7907):763-770）。
四、研究成果
1. Yu-Qi Ping#, Peng Xiao#, Fan Yang#, Ru-Jia Zhao#, Sheng-Chao Guo#, Xu Yan#, Xiang Wu#, Chao Zhang, Yan Lu, Fenghui Zhao, Fulai Zhou, Yue-Tong Xi, Wanchao Yin, Feng-Zhen Liu, Dong-Fang He, Dao-Lai Zhang, Zhong-Liang Zhu, Yi Jiang, Lutao Du, Shi-Qing Feng, Torsten Schöneberg, Ines Liebscher*, H. Eric Xu* & Jin-Peng Sun*. Structural basis for the tethered peptide activation of adhesion GPCRs. Nature. 2022 Apr;604(7907):763-770.
2. Yu-Qi Ping#, Chunyou Mao#, Peng Xiao#, Ru-Jia Zhao#, Yi Jiang#, Zhao Yang, Wen-Tao An, Dan-Dan Shen, Fan Yang, Huibing Zhang, Changxiu Qu, Qingya Shen, Caiping Tian, Zi-jian Li, Shaolong Li, Guang-Yu Wang, Xiaona Tao, Xin Wen, Ya-Ni Zhong, Jing Yang, Fan Yi, Xiao Yu, H. Eric Xu*, Yan Zhang* & Jin-Peng Sun*. Structures of the glucocorticoid-bound adhesion receptor GPR97-Go complex. Nature. 2021 Jan;589(7843):620-626.
合作发表文章：
1. Fan Yang#, Chunyou Mao#, Lulu Guo#, Jingyu Lin#, Qianqian Ming#, Peng Xiao#, Xiang Wu#, Qingya Shen, Shimeng Guo, Dan-Dan Shen, Ruirui Lu, Linqi Zhang, Shenming Huang, Yuqi Ping, Chenlu Zhang, Cheng Ma, Kai Zhang, Xiaoying Liang, Yuemao Shen, Fajun Nan, Fan Yi, Vincent C Luca, Jiuyao Zhou, Changtao Jiang, Jin-Peng Sun*, Xin Xie*, Xiao Yu*, Yan Zhang*. Structural basis of GPBAR activation and bile acid recognition. Nature. 2020 Nov; 587(7834):499-504.
2. Lin H#, Xiao P#, Bu RQ#, Guo S#, Yang Z#, Yuan D#, Zhu ZL, Zhang CX, He QT, Zhang C, Ping YQ, Zhao RJ, Ma CS, Liu CH, Zhang XN, Jiang D, Huang S, Xi YT, Zhang DL, Xue CY, Yang BS, Li JY, Lin HC, Zeng XH, Zhao H, Xu WM, Yi F, Liu Z, Sun JP#, Yu X#. Structures of the ADGRG2-Gs complex in apo and ligand-bound forms. Nat Chem Biol 18, 1196–1203 (2022)
五、联系方式
欢迎有科研愿望的老师、同学加入团队。联系方式：pingyuqi@126.com
