一、个人简介

教授，博士生导师，山东省泰山学者青年专家。2014年于厦门大学获得细胞生物学博士学位；2015年至2016年在山东大学药学院进行博士后研究工作；2016年至2022年在山东师范大学生命科学学院工作；2023年任职于山东第一医科大学医学科技创新中心。

二、研究领域

主要研究领域为利用细胞、动物模型等来探索细胞间互作与皮肤疾病发生。

三、项目、获奖及荣誉情况概述

先后承担国家自然科学基金面上项目、国家自然科学基金青年科学基金项目、山东省自然科学基金面上项目等。相关研究发表在Cell Reports、Signal Transduction and Targeted Therapy、Autophagy、Journal of Biological Chemistry、Journal of Genetics and Genomics、Journal of Cellular Physiology等国际主流期刊。

四、代表性研究成果

1. Xie, Wei#, Gao, Siqi#, Yang, Yunfan*, Li, Hongjie, Zhou, Junyan, Chen, Mingzhen, Yang, Song, Zhang, Yijun, Zhang, Liang, Meng, Xiaoqian, Xie, Songbo, Liu, Min, Li, Dengwen, Chen, Yan, and Zhou, Jun* (2022). CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart. Cell Reports, 41, 111864. 10.1016/j.celrep.2022.111864. (IF: 9.995)

2. Xie, Wei, Chen, Mingzhen, Zhai, Zhaodong, Li, Hongjie, Song, Ting, Zhu, Yigao, Dong, Dan, Zhou, Peng, Duan, Liangwei, Zhang, You, Li, Dengwen, Liu, Xinqi, Zhou, Jun, and Liu, Min* (2021). HIV-1 exposure promotes PKG1-mediated phosphorylation and degradation of stathmin to increase epithelial barrier permeability. Journal of Biological Chemistry 296, 100644. 10.1016/j.jbc.2021.100644. (IF: 5.486)

3. Xie, Wei, Li, Dengwen*, Dong, Dan, Li, Yuanyuan, Zhang, You, Duan, Liangwei, Liu, Xinqi, Meng, Wenxiang, Liu, Min, and Zhou, Jun* (2020). HIV-1 exposure triggers autophagic degradation of stathmin and hyperstabilization of microtubules to disrupt epithelial cell junctions. Signal Transduction and Targeted Therapy 5, 79. 10.1038/s41392-020-0175-1. (IF: 38.104)

4. Xie, Wei#, Yang, Yunfan#, Gao, Siqi, Song, Ting, Wu, Yuhan, Li, Dengwen, Liu, Min, and Zhou, Jun* (2017). The tumor suppressor CYLD controls epithelial morphogenesis and homeostasis by regulating mitotic spindle behavior and adherens junction assembly. Journal of Genetics and Genomics 44, 343-353. 10.1016/j.jgg.2017.06.002. (IF: 5.723)

5. Xie, Wei, Zhang, Lei, Jiao, Haifeng, Guan, Li, Zha, Junmin, Li, Xiaotong, Wu, Mian, Wang, Zhanxiang, Han, Jiahuai, and You, Han* (2015). Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA. Autophagy 11, 1623-1635. 10.1080/15548627.2015.1075688. (IF: 13.391)

五、联系方式

课题组长期招收研究生和博士后，欢迎加盟！

地址：医学科技创新中心D311；邮箱：xiew@sdfmu.edu.cn