一、个人简介

研究聚焦于糖尿病及心血管疾病的分子标志物及防治靶点研究，重点探索组织微环境及细胞和器官间通讯，近年来致力于心血管及糖尿病大规模人群队列建设、人群胰岛β细胞功能评估，结合代谢组学、蛋白组学等多组学技术探究心血管及糖尿病的发生机制和新型治疗靶点，深入解析细胞通讯、氨基酸转运代谢稳态在糖尿病、心血管疾病发生过程中的作用，为疾病防治提供理论依据。曾入选 “博士后创新人才支持计划”，广东省优秀研究生、中山大学优秀毕业生、优秀博士毕业论文获得者。近5年主持国家自然科学基金青年项目、山东省自然科学基金、博士后面上项目等，并参与中国科学院先导计划、重点研发计划等多个项目；代表性论文发表于Diabetes Care、Diabetes、Diabetology、Journal of Hepatology、 iMetaomics等，申请国家发明专利 3项。

二、代表论著

1.Fengling Lai, Kaixin Zhou, Yingjie Ma, Hao Lv, Weilin Wang, Rundong Wang, Tao Xu*, Rong Huang*. Single-Cell Rna Sequencing Identifies Endothelial-Derived Hbegf as Promoting Pancreatic Beta Cell Proliferation in Mice Via the Egfr–Kmt5a–H4k20me Pathway. Diabetologia Published online 2024 December. (Article，共同通讯作者，IF=8.4，中科院1区)

2.Lingjun Tong, Qiyue Wang, Yameng Zhang, Fengling Lai, Jiarun Xu, Wenchao Yin, Sitong Zhang, Guoyue Wei, Jie Yin, Huaxi Yi, Gert Storm, Zhaoyang Wang*, Rong Huang*, Tao Xu*, Jiong-Wei Wang*. Myocardial Delivery of Mir30d with Peptide-Functionalized Milk-Derived Extracellular Vesicles for Targeted Treatment of Hypertrophic Heart Failure. Biomaterials 2024 Nov; 316:122976.(Article，共同通讯作者，IF=12.8，中科院1区)

3.Rong Huang, Songping Yin, Yongxin Ye, Nixuan Chen, Shiyun Luo, Min Xia*, Lina Zhao*. Circulating Retinol-Binding Protein 4 Is Inversely Associated with Pancreatic Β-Cell Function across the Spectrum of Glycemia. Diabetes Care 2020 Apr; 1258-65. (Article，独立第一作者，IF=14.8，中科院1区)

4.Rong Huang, Xinxiu Bai, Xiaohui Wang, Min Xia*, Lina Zhao*. Retinol-Binding Protein 4 Activates STRA6 Provoking Pancreatic β Cell Dysfunction in Type 2 Diabetes. Diabetes 2021;70(2):449-463. (Article，独立第一作者，IF=6.2，中科院1区)

5.Rong Huang^#, Jie Li^#, Keqing Hu, Rui Xu, Haitao Yuan, Jiangrong Wang, Mei Gao, Qiang Xiao, Bingqing Dong, Furen Zhang, Fengling Lai, Luxiang Shang, Siyu Hou, Lingjun Tong, Kaixin Zhou, Guohai Su*, Tao Xu*. Cohort Profile: A Longitudinal Multi‐Omics Cohort of Patients with Acute Coronary Syndrome. iMetaOmics 2024;1: e18.(Article，共同第一作者，New)

6.Shen Chen^#, Hongliang Xue^#, Rong Huang^#, Ke Chen, Haoyang Zhang, Xu Chen. Associations of Mafld and Mafld Subtypes with the Risk of the Incident Myocardial Infarction and Stroke. Diabetes & Metabolism 2023;49(5):101468.(Article，共同第一作者，IF=4.6)

7.Xu Chen, Shen Chen, Juan Pang, Rong Huang, Yiran You, Haoyang Zhang, Jinghe Xiao, Hongliang Xue*, Wenhua Ling*. Hepatic Steatosis Aggravates Atherosclerosis Via Small Extracellular Vesicle-Mediated Inhibition of Cellular Cholesterol Efflux. Journal of Hepatology 2023;79(6):1491-1501. (Article，合作作者，IF=26.8)

8.Shen Chen, Juan Pang, Rong Huang, Yiran You, Haoyang Zhang, Hongliang Xue, Xu Chen*. Associations of Macronutrients Intake with MRI-Determined Hepatic Fat Content, Hepatic Fibroinflammation, and Nafld. The Journal of Clinical Endocrinology & Metabolism 2023;108(12):e1660-e1669. (Article，合作作者，IF=5)

9.Yiming Guo, Jing Zhao, Rong Huang, Tao Xu*, Kaixin Zhou*, Li Zheng*. Scalable Dual-Fluorescence Assay for Functional Interpretation of Hnf-4α Missense Variants. Frontiers in Endocrinology 2022;13:812747. (Article，合作作者，IF=3.9)

10.Lingjun Tong*, Sitong Zhang, Rong Huang*, Huaxi Yi, Jiong-Wei Wang. Extracellular Vesicles as a Novel Photosensitive Drug Delivery System for Enhanced Photodynamic Therapy. Frontiers in Bioengineering and Biotechnology 2022;10:1032318.(Article，合作作者，IF=4.3)

三、招生要求

学术型:偏向流行病与卫生统计学、营养与食品卫生学、心血管疾病、分子生物学等方向

专业型:偏向公共卫生方向-基于多组学筛查心血管疾病分子标志物