仝令君 副教授

学历/学位:研究生学历/博士学位
研究方向:纳米医学(代谢性相关心血管疾病)
邮箱:ljtong@sdfmu.edu.cn / m18754030882@163.com

一、个人简介

仝令君,副教授,泰山学者青年专家,科创中心徐涛院士工作站骨干,硕士生导师。博士毕业于中国海洋大学,曾在新加坡国立大学(NUS)杨潞龄医学院,纳米医学中心A*STAR进行科研训练。主要研究方向为:(1)心血管疾病新型生物标志物的筛选;(2)基于外泌体作为药物载体的精准靶向治疗;(3)外泌体大规模生产技术的开发与应用。

目前主持国家自然基金青年项目1项,山东省自然科学基金青年和面上项目共2项,山东省泰山学者青年项目1项。近5年,以第一作者或通讯作者分别在Science Advances(高被引),Journal of Extracellular VesiclesTheranostics(高被引,封面文章),Advanced Drug Delivery Reviews(高被引),Biomaterials等国际知名期刊发表SCI数十篇,其中5篇IF > 10,并获得国际PCT发明专利1项(排名第二位)。主要学术兼职:美国细胞外囊泡官方会刊《Extracellular Vesicle》青年编委;国际液体活检官方会刊《Extracellular Vesicles and Circulating Nucleic Acids》青年编委;国际细胞外囊泡协会(ISEV)Milk Task Force成员;中国研究型医院学会细胞外囊泡研究与应用委员会青年委员;山东省健康管理协会微生态医学专业委员会常务委员。

二、代表论著

1. Tong L#, Wang Q#, Zhang Y, Lai F, Xu J, Yin W, Zhang S, Wei G, Yin J, Yi H, Storm G, Wang Z*, Huang R*, Xu T*, Wang JW*. Myocardial delivery of miR30d with peptide-functionalized milk-derived extracellular vesicles for targeted treatment of hypertrophic heart failure. Biomaterials. 2025 May;316:122976. (IF=12.8)

2. Zhang S, Wang Q, Tan DEL, Sikka V, Ng CH, Xian Y, Li D, Muthiah M, Chew NWS, Storm G, Tong L*, Wang JW*. Gut-liver axis: Potential mechanisms of action of food-derived extracellular vesicles. Journal of Extracellular Vesicles. 2024 Jun;13(6):e12466. (IF=15.5)

3. Zhang S, Sun X, Zhang Y, Huang R, Situ W, Yi H*, Tong L*. Metabolomics analysis of extracellular vesicles derived from bovine colostrum and mature milk. Food Science of Animal Products, 2024, 2(3): 9240078.

4. Tong L#, Zhang S#, …., Muthiah M, Pastorin G, Wacker MG, Chen X, …, Yi H*, Wang JW*. Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis. Science Advances. 2023 Apr 14;9(15): eade5041. (IF=14.957,高被引)

5. Zhang S, Li D, …, Tong L*, Xu L*. Multifunctional exosome-driven pancreatic cancer diagnostics and therapeutics. Extracellular Vesicle. 2023 Dec; 2, 100022.

6. Tong L*, Zhang S, Huang R*, Yi H, Wang JW. Extracellular vesicles as a novel photosensitive drug delivery system for enhanced photodynamic therapy. Frontiers in Bioengineering and Biotechnology. 2022 Sep 27;10:1032318.

7. Tong L, Hao H, …, Pastorin G, Lee CN, Chen X, Wang JW*, Yi H*. Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota. Theranostics. 2021 Jul 25;11(17):8570-8586. (IF=12.4, 封面文章,高被引,被引190次)

8. de Castilla EMP#, Tong L#, Huang C#, …, Storm G, Schiffelers RM, Wang JW. Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies. Advanced Drug Delivery Reviews. 2021 Aug; 175: 113801. (IF=17.873, 高被引,被引162次)

9. Tong L, Zhang X, Hao H, Liu Q, Zhou Z, Liang X, Liu T, Gong P, Zhang L, Zhai Z, Hao Y, Yi H. Lactobacillus rhamnosus GG Derived Extracellular Vesicles Modulate Gut Microbiota and Attenuate Inflammatory in DSS-Induced Colitis Mice. Nutrients. 2021 Sep 23;13(10):3319.

10. Tong L, Hao H, …, Yi H*. Oral Administration of Bovine Milk-Derived Extracellular Vesicles Alters the Gut Microbiota and Enhances Intestinal Immunity in Mice. Molecular Nutrition & Food Research. 2020 Apr; 64(8): e1901251. (IF=6.575, 封面文章,被引117次)

三、招生要求

学术型:偏向纳米医学方向(心血管疾病精准靶向治疗)

专业型:偏向慢性病预防和控制方向


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