一、个人简介

郑润晓，硕士生导师，博士后导师，毕业于中国科学院长春应用化学研究所，主要基于 NLRP3 炎性体或炎症调控，采用生物正交、Crisper/Cas 9 等方式开展缺血性脑卒中、阿尔兹海默症、脑膜炎等脑部疾病治疗研究，且围绕NLRP3炎性体机制，探索其在环境毒理学效应及其调控作用，形成 “机制解析 - 毒理关联 - 疾病干预” 系统框架。主持国家自然科学基金青年项目及国家外专项目两项国家级项目，以及山东省自然科学基金，山东省中医药项目及海外客座教授支持计划项目等。

二、代表论著

1. Runxiao Zheng#, Chengzhilin Li#, Changshun Huang, Qingbin He, et.al, Vadim V. Shmanai, Ming Xia*, Jianwei Jiao*, Haiyuan Zhang*, Sequentially regulated Lysosomal Assembly Formation and Degradation for Potent Inflammasome Driven Immunotherapy, Small, 2025, 21, e06341. (IF=12.1)

2. Chengzhilin Li, Nianlei Zhang, Ziang Xu, et.al, Yachao Zhang, Yue Hua, Houyang Hu, Qingbin He, Vadim V. Shmanai, Ming Xia, Haiyuan Zhang, Miaoqing Zhao*, Jianwei Jiao*, Runxiao Zheng*, Inflammasome mediated in situ cancer vaccine activated by Schottky heterojunction for augmented immunotherapy, Journal of Control Release, 2025, 380, 1184-1197. (IF=11.5)

3. Chengzhilin Li#, Fanyu Yuan#, LiHang Lou, Ziang Xua, Nianlei Zhang, Changshun Huang, Xinyu Wang, Wenyu Zhang, Tingjian Zua*, Ming Xia*, Runxiao Zheng*, Mitochondrial Stress Primed cGAS-STING Activation Synergized with NF-κB Signaling for Enhanced Antitumor Immunotherapy, Chemical Engineering Journal, 2026, accept. (IF=13.3)

4. Wenyu Zhang, Changshun Huang, Chengzhilin Li, Xinyu Wang, Ying Qu, Wenlong Duan, Yingyu Hou, Yingchun Zhao, Qingbin He, Jianwei Jiao*, Zhengwei Liu*, Runxiao Zheng*, Self-amplifying pyroptosis nanoinducers enhance cancer immunotherapy through inflammasome priming and activation, Journal of Controlled Release, 2026, 392, 114689. (IF=11.5)

5. Yingchun Zhao, Ying Qu, Changshun Huang, Chengzhilin Li, Wenyu Zhang, Xinyu Wang, Wenlong Duan, Qingbin He, Yachao Zhang*, Jianwei Jiao*, Runxiao Zheng*, Neutrophils loaded NAD+ impede TLR4/NF-κB/NLRP3 pathway for sepsis treatment, Materials Today Bio, 2025, 34, 102168. (IF=10.2)

6. Chaoran Liu#, Wenyu Zhang#, Qingbin He, Xinyu Ma, Jianfeng Qiu, Runxiao Zheng*, Hongjin Xue*, Unraveling the structure-activity relationship of alloying in nanozyme design for synergistic tumor metabolic-immunotherapy, Journal of Nanobiotechnology, 2026, 24,135. (IF=12.6)

7. Meng Zhang, Yinchuan Wang, Xueling Yin, Mei Xue, Xin Zhao, Runxiao Zheng*, Jianfeng Qiu*, Zhihong Zhu*, Chlorogenic acid-assisted dopamine‑sodium alginate composite nanofiber membranes for promoting wound healing, Carbohydrate Polymers, 2025, 354, 123298. (IF=12.5)

8. Runxiao Zheng, Yan Cheng*, Fan Qi, Yunyun Wu, Xiaoqing Han, Jiao Yan, Haiyuan Zhang*, Biodegradable Copper-Based Nanoparticles Augmented Chemodynamic Therapy through Deep Penetration and Suppressing Antioxidant Activity in Tumors, Advanced Healthcare Materials, 2021, 2100412. (IF=9.6)

9. Runxiao Zheng, Liming Wang, Xiaqing Wu, Panpan Song, Yanjing Wang, Haiyuan Zhang*, Biotransformation of soluble-insoluble lanthanum species and its induced NLRP3 inflammasome activation and chronic fibrosis, Environmental Pollution, 2021, 284, 11748. (IF=9.98)

10. Runxiao Zheng, Jing Zhang, Xiaoqing Han, Yunyun Wu, Jiao Yan, Panpan Song, Yanjing Wang, Xiaqing Wu and Haiyuan Zhang*, Particulate matter aggravates Alzheimer's disease by activating the NLRP3 inflammasome to release ASC specks, Environmental Science Nano, 2021, 8, 2177-2190. (IF=9.4)

三、招生要求

学术型：偏向细胞生物学方向

专业型：偏向药学方向