一、 个人简介
孙文龙,教授,生物医学工程博士,山东省“泰山学者”青年专家、山东省高等学校“青创计划”团队带头人。从事·代谢性疾病的中药(中西医结合)干预与病理机制研究。以第一或通讯作者发表SCI论文32篇,其中包括CNS高影响力子刊3篇(Cell Discovery杂志论文1篇、Nature Communications杂志论文1篇、Cell Reports杂志论文1篇)、Gut Microbes杂志论文1篇、Coordination Chemistry Reviews杂志论文1篇,共计ESI高被引论文7篇、热点论文3篇、IF>10论文8篇,最高影响因子23.5,单篇最高被引363,总被引1741次,H指数23。主持国家级项目4项和省部级项目3项,作为科研骨干参与国家重点研发计划“中医药现代化”重点专项等国家级项目。荣获中国民族医药学会科学技术奖一等奖、淄博市重大科技成果奖1项、中国山东博士后创新创业大赛优秀奖1项、中国药学会年会优秀论文奖1项;参编团体标准3项;申请国家发明专利12项、授权国家发明专利5项和实用新型专利4项。
二、 代表论著
1. Wenlong Sun1, Sha Hua1, XinYu Li, Liang Shen*, Hao Wu*, Hong-Fang*. Microbially produced vitamin B12 contributes to the lipid-lowering effect of silymarin. Nature Communications, 2023, 14:477.
2. Li, L.1, Li, T.1, Liang, X,1, Zhu, L.1, Fang, Y., Dong, L., Zheng, Y., Xu, X., Li M., Cai, T., Zhao F., Xin, M., Shao, M., Guan, Y., Liu, M., Li, F., Zhang, C.*, Wang, Q.*, Sun, W.*, Zheng, Y.* A decrease in Flavonifractor plautii and its product, phytosphingosine, predisposes individuals with phlegm-dampness constitution to metabolic disorders. Cell Discovery, 2025.
3. Wenlong Sun, Xinyu Li, Haoyue Dou, Xudong Wang, Jingda Li, Liang Shen*, Hongfang Ji*, Myricetin supplementation decreases hepatic lipid synthesis and inflammation by modulating gut microbiota. Cell reports, 2021, 36(9), 109641.
4. Jinghan Jia1, Shuyue Zhai1, Tianqi Cai, Pingping Guo, Gangao Yang, Zukang Chang, Yongning Chen, Xinhua Song, Xueyao Lu, Le Chu, Fatao He, Maoyu Wu, Guangpeng Liu*, Wenlong Sun* Rutin alleviates high-fat diet-induced MAFLD: insights from 16S rRNA sequencing, metabolome, network pharmacology and transcriptome analyses. Food Science and Human Wellness 15 (2026) 9250908
5. Wang, Y., Huang, B., Wei, X., Guan, Y., Li, L.*, Zheng, Y.*, Sun, W.* Gut Microbiota Metabolic Reprogramming Drives the Development of Metabolic Diseases in the Host. Gut Microbes, 2026, accept
6. Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang*, Meng-Yao Li*, Wenlong Sun* SUMOylation Regulates Tumorigenesis and Progression: Molecular Mechanisms and Therapeutic Applications, Interdisciplinary Medicine
7. Jingda Li*, Tianqi Wang, Panpan Liu, Fuyuan Yang, Xudong Wang, Weilong Zheng and Wenlong Sun* Hesperetin ameliorates hepatic oxidative stress and inflammation via the PI3K/AKT-Nrf2-ARE pathway in oleic acid-induced HepG2 cells and a rat model of high-fat diet-induced NAFLD. Food & Function.2021, 12(9), 3898-3918.
8. Bendong Yang, Meiling Xin, Shufei Liang, Yuhong Huang, Jingda Li, Chao Wang, Chao Liu, Xinhua Song*, Jinyue Sun*, and Wenlong Sun*. Naringenin Ameliorates Hyperuricemia by Regulating Renal Uric Acid Excretion via the PI3K/AKT Signaling Pathway and Renal Inflammation through the NF-κB Signaling Pathway. J. Agric. Food Chem. 2023, 71, 1434−1446.
9. Wenlong Sun*, Panpan Liu, Bendong Yang, Meng Wang, Tianqi Wang, Wenbo Sun, Xudong Wang, Weilong Zheng, XinhuaSong*, JingdaLi*. A network pharmacology approach: inhibition of the NF-κB signaling pathway contributes to the NASH preventative effect of an Oroxylum indicum seed extract in oleic acid-stimulated HepG2 cells and high-fat diet-fed rats Phytomedicine, 2021,88, 153498.
10. Xiaoxue Xu1, Yanrong Wang1, Xiaofei Wu, Tianqi Cai, Ling Dong, Shufei Liang, Linghui Zhu, Xinhua Song, Yang Dong, Yanfei Zheng*, Lingru Li*, Wenlong Sun*, Administration of Alistipes indistinctus prevented the progression from nonalcoholic fatty liver disease to nonalcoholic steatohepatitis by enhancing the gut barrier and increasing Lactobacillus spp. Biochemical and Biophysical Research Communications 741 (2024) 151033
三、招生要求
学术型:
博士:基础医学;病理学与病理生理学
硕士:药学:药理学
专业型:
硕士:药学